Heart

Heart

High Sensitivity Troponin in Familial Hypercholesterolemia

Familial Hypercholesterolemia (FH) is a common hereditary condition which affects approximately 1 in 500 people in the UK. It leads to unusually high levels of cholesterol in the blood and...

Treatment Adherence in Coronary Heart Disease: Understanding the Efficacy-effectiveness gap in patient medication and rehabilitation use

Evidence suggests that after an acute coronary event patients beliefs and adherence to cardiac rehabilitation (CR) can be impacted by their partners’ beliefs and behaviours. This study aims to assess...

How Can Pharmacy Help Patients with Heart Failure who Struggle to Manage Their Medicines and Condition?

When patients with heart failure do not take their medicines as directed, they become sicker and die earlier. As is often the case, patients from deprived areas are more likely...

The Effect of Acute UV-A Exposure and Dietary Nitrate Ingestion on Plasma Nitrate, Endothelial Function and Blood Pressure

This pilot project will explore whether two methods of increasing levels of nitric oxide in the body will enhance key markers of cardiovascular health. Specifically, we will investigate the acute...

Diagnostic Yield of an Ambulatory Patch Monitor in Emergency Department Syncope Patients Unexplained after Emergency Department Evaluation- a Pilot Study (PATCH-ED)

Syncope (blackout) is a common Emergency Department (ED) problem but the diagnosis is not apparent in two third of patients. Serious outcome is 7% at one month and 15% at...

Assessing the predictive value of quantitative high throughput NMR metabolomic analysis for CVD events in a major diabetes trial: ADVANCE

Cutting-edge technology is being harnessed to give a more detailed analysis of the chemical make-up of blood samples than has yet been possible. The research team has developed the ability...

An investigation of the role of thrombin generation as a marker of increased risk of thromboembolic stroke in patients with atrial fibrillation

Metabolic Imaging in Carotid Atherosclerosis (MICA Study)

Many heart attacks and strokes are caused by the common condition of atherosclerosis – hardening of the arteries. New ways of imaging this disease, using PET and MRI scanning, are...

Optimisation of pre-hospital resuscitation in out-of-hospital cardiac arrest using a novel method of resuscitation analysis to facilitate training and performance evaluation

Surviving an out-of-hospital cardiac arrest (OHCA), brought on by a heart attack, depends on high quality resuscitation before the patient reaches hospital. Such treatment is highly complex and requires specific...

The Association Between Blood Pressure and the Different Pathological Types of Stroke in UK Biobank

My project will use data from the UK Biobank, a detailed study of 500,000 volunteers, to improve our understanding of the relationships between different measures of blood pressure (BP) and...